LipL21 lipoprotein binding to peptidoglycan enables Leptospira interrogans to escape NOD1 and NOD2 recognition.

Although these results did not reach statistical significance, this trend suggests a slight better clearance of the M58 strain compared to the C5M58 expressing LipL21, which is in contrast with the results showing no difference of clearance of M58 and C5M58 in WT mice ( Fig 5A ).

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