Methylene-tetrahydrofolate reductase contributes to allergic airway disease.

In order to more directly measure the relationship between methylation and expression, correlation was tested between nominally significant DMRs (n = 6,927) and expression probes within 1 Mb (n = 54,611). 503 significant relationships (corrected p-value <0.05) were identified between expression and methylation data consisting of 354 unique methylation clusters and 491 expression probes ( S5 Table ).

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