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Atypical E2Fs inhibit tumor angiogenesis.

Oncogene · 2018 · PMC5770600 · PMID 28925392

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We found that deletion of E2f7/8 both in vitro and in engrafted tumors, resulted in decreased expression of the Notch ligand Dll4 , and of the Dll4/Notch1 target Hey1 , however the latter did not reach statistical significance ( Figures 4b and c ).

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