Oncogenic dependency on β-catenin in liver cancer cell lines correlates with pathway activation.

Kaplan-Meier analysis revealed a trend toward worse survival for HCC patients with exclusively nuclear β-catenin (“β-catenin activation”) versus those with no detectable nuclear staining (“No β-catenin activation”), although it did not reach statistical significance (log-rank test p = 0.08) ( Supplementary Figure 1 ).

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