Defective STIM-mediated store operated Ca²⁺ entry in hepatocytes leads to metabolic dysfunction in obesity.

In long term HFD (20 weeks), the differences in glucose intolerance, insulin signaling and Tg content between stim1 fl/fl and stim1Δ LIVER groups were very mild and did not reach statistical significance ( Figure 3—figure supplement 2F,G and H ).

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