The relationship between telomere length and mortality risk in non-model vertebrate systems: a meta-analysis.

Philos Trans R Soc Lond B Biol Sci · 2018 · PMC5784067 · PMID 29335371

Europe PMC DOI

hedged sentences

0.0630

closest p · 1.3× alpha

0.0830

boldest claim

The sentences

marginally non-significantp = 0.063so close (0.05 < p ≤ 0.1)

We found a similarly negative and significant overall effect (−0.224 ± 0.050; p < 0.001), but the method moderator effect became weaker and marginally non-significant in this dataset (difference TRF–qPCR: −0.184 ± 0.099; p = 0.063), suggesting that the strongly positive TL–mortality risk estimate from the python study was at least in part responsible for the method effect we observed. 4.

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marginally significantp = 0.083so close (0.05 < p ≤ 0.1)

We also applied the ‘trim and fill’ method [ 55 ] to examine the sensitivity of the results to publication bias and found that the overall association became substantially weaker and remained marginally significant (−0.108 ± 0.062 s.e.; p = 0.083).

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a suggestive trendno p-value reported

In our analyses, we found a suggestive trend for weaker TL–mortality risk associations in reptiles compared to birds that may have been driven by a single outlying study.

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