However, when the cell lines were stratified into GCB and non-GCB subsets, in ixazomib-treated cells the GCB subset showed a trend toward a positive correlation for the c-proteasome subunits and a negative correlation for the i-proteasome subunits, particularly MECL-1 (Figure 3A ).
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Preclinical efficacy and biological effects of the oral proteasome inhibitor ixazomib in diffuse large B-cell lymphoma.
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