Barely Significant
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<i>PD-L1</i> (<i>CD274</i>) and <i>PD-L2</i> (<i>PDCD1LG2</i>) promoter methylation is associated with HPV infection and transcriptional repression in head and neck squamous cell carcinomas.

Oncotarget · 2018 · PMC5787495 · PMID 29416641

1
hedged sentence
0.0770
closest p · 1.5× alpha
0.0770
boldest claim

The sentences

showed a trendp = 0.077so close (0.05 < p ≤ 0.1)
PD-L1 methylation levels only showed a trend towards lower methylation in tumors versus NATs (median methylation in tumors: 2.34%, NATs: 3.28%, p = 0.077, Mann-Whitney U test).

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