Barely Significant
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Plasma concentration of selected biochemical markers of endothelial dysfunction in women with various severity of chronic venous insufficiency (CVI)-A pilot study.

PLoS One · 2018 · PMC5788369 · PMID 29377939

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a significant trendno p-value reported
Our study demonstrates a high concentration of sTM in CVI women which shows a significant trend to rise together with disease severity.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.