Consistently, high CD49d expression, the presence of TP53 disruption, and UM IGHV gene status (which did not reach statistical significance) identified a patient subset with shorter PFS intervals in the context of the RR cohort ( Fig. 7, G–I ).
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Functional and clinical relevance of VLA-4 (CD49d/CD29) in ibrutinib-treated chronic lymphocytic leukemia.
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