Early bone tissue aging in human auditory ossicles is accompanied by excessive hypermineralization, osteocyte death and micropetrosis.

Sci Rep · 2018 · PMC5789841 · PMID 29382878

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a significant trendp = 0.001actually significant

Mineralization and osteocyte parameters of the malleus Quantitative backscattered electron imaging showed a significant trend of increasing mineral content of the bone matrix with age (logarithmic fit: r 2 = 0.559, p = 0.001; Fig. 4A ).

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