Curcumin-mediated bone marrow mesenchymal stem cell sheets create a favorable immune microenvironment for adult full-thickness cutaneous wound healing.

In the CS-C group in our study, during the early stage of repair, there was a strong trend towards T H 2 activation (0–7 days) and M2 polarization (7–14 days) and, fortunately, at the later stage (after 14 days), the number of M2 macrophages fell (Fig. 7e ).

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