Knockdown of wfs1, a fly homolog of Wolfram syndrome 1, in the nervous system increases susceptibility to age- and stress-induced neuronal dysfunction and degeneration in Drosophila.

PLoS Genet · 2018 · PMC5794194 · PMID 29357349

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did not reach statistical significanceno p-value reported

Although there was a trend that wfs1 expression slightly suppressed retinal degeneration induced by tau, they did not reach statistical significance ( S9 Fig ).

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