JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche.

The 4-week expression of GFP-CAG-NLS-JBD or GFP-CAG-NES-JBD did not alter immobility time in this test of behavioural despair ( Figure 6f ), although there was a slight trend.

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When tested for sucrose preference, an indicator of anhedonic state in rodents, Jnk1−/− mice showed a trend towards increased sucrose intake ( Figure 1k ).

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