showed a trendP = 0.07
The latter study also showed a trend for more aggressive disease progression in patients with steatosis and mild inflammation compared to patients with isolated steatosis ( P = 0.07). 24 In our study with a mean follow‐up time of 19.8 years, fibrosis progression ≥1 stage was seen in 61% (22 out of 36) of patients with isolated steatosis at inclusion, of whom 5 patients developed advanced fibrosis or end‐stage liver disease.