Proteins of TNF-α and IL6 Pathways Are Elevated in Serum of Type-1 Diabetes Patients with Microalbuminuria.

Comparison of the mean expression levels between T1D and MA groups revealed highly significant differences for six proteins (sTNFR1, sTNFR2, sIL2Rα, MMP2, sIL6R, and sgp130; P < 1 × 10 −5 ) and moderately significant differences for four proteins (CRP, SAA, sICAM1, and sVCAM1; P < 0.05) (Table S1 in Supplementary Material).

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