The significance of tumour microarchitectural features in breast cancer prognosis: a digital image analysis.

Breast Cancer Res · 2018 · PMC5799893 · PMID 29402299

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0730

boldest claim

The sentences

showed a trendp = 0.06so close (0.05 < p ≤ 0.1)

Similar to BCSS, triple-negative cancers showed a trend for cases with higher number of nests to present with higher risk of distant metastasis (HR per 1 SD increase 1.45, 95% CI 0.98 to 2.15; p = 0.06; Fig. 4b ).

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borderline significantp = 0.073so close (0.05 < p ≤ 0.1)

1a and 2 ) and borderline significant in grade 1 tumours (OR per 1 SD 1.83, 95% CI 0.94 to 3.56, p = 0.073).

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highly significantno p-value reported

Our data indicate that this is the most highly significant tumour microarchitectural predictor of survival, consistent with the previously proposed role of the tumour-stroma interface in the pathogenesis of breast cancer metastasis, and its promise as a therapeutic target [ 30 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.