MORG1^+/- mice are protected from histological renal damage and inflammation in a murine model of endotoxemia.

We further evaluated the renal gene expression of the mainly HIF2-α regulated gene erythropoietin in whole renal homogenates and found that its basal and LPS-dependent induction was numerically increased in the MORG1 heterozygous animals compared to the MORG1 +/+ mice, but did not reach statistical significance (Fig. 4d ).

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