TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD.

Nat Neurosci · 2018 · PMC5800968 · PMID 29311743

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showed a trendno p-value reported

The distribution pattern of Nup205 was altered in C9-ALS and TDP-ALS fibroblasts, which exhibited significantly increased abnormal lamin B staining (17% and 22%), whereas sALS cells showed a trend for increase ( Fig. 5c, d ).

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