Blunting of cardioprotective actions of estrogen in female rodent heart linked to altered expression of cardiac tissue chymase and ACE2.

J Renin Angiotensin Aldosterone Syst · 2017 · PMC5805468 · PMID 28748720

Europe PMC DOI

hedged sentence

0.0550

closest p · 1.1× alpha

0.0550

boldest claim

The sentences

a strong trendp = 0.055so close (0.05 < p ≤ 0.1)

There was also a strong trend for an association between elevated filling pressures and a reduction in cardiac ACE2 activity ( p = 0.055), as 66% of the variance in E/e′ could be inversely attributed to ACE2 (the Ang-(1-7)-forming enzyme).

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