A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques.

J Virol · 2018 · PMC5809733 · PMID 29237847

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a strong trendno p-value reported

A strong trend was observed between the overall anti-gp120 response and V1V2-directed antibodies in cycP-gp120-immunized rabbits, a correlation not found in gp120-immunized rabbits ( Fig. 2C ), indicating that cycP-gp120 can preferentially promote V1V2 antibodies as part of the overall antibody response against HIV-1 Env.

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