Vaccination of calves with Mycobacterium bovis Bacillus Calmette-Guerin reduces the frequency and severity of lesions of bovine tuberculosis under a natural transmission setting in Ethiopia.

Similarly, increased IFN‐γ responses in VL compared to NVL animals were observed in the BCG‐vaccinated animals when this parameter was determined at 4 to 12 months of the exposure period (Figure 3 b–f), although due to one outlying response, these differences were not or not quite statistically significant ( p values of 0.07 to 0.26, Figure 3 ).

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While we observed similar reductions in the severity of gross pathology in vaccinated calves also in head lymph nodes and the lungs compared to unvaccinated controls, these reductions did not reach statistical significance (Figure 4 ).

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