Systematic review of model-based economic evaluations of heart valve implantations.

Eur J Health Econ · 2018 · PMC5813051 · PMID 28265822

Europe PMC DOI

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a clear trendno p-value reported

Our results did not reflect a clear trend in the cost-effectiveness of heart valve implantations over time; probably due to the short time frame in which the studies were performed (>80% in 2012–2013).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.