Chronic ET<sub>A</sub> antagonist reverses hypertension and impairment of structure and function of peripheral small arteries in aortic stiffening.

Sci Rep · 2018 · PMC5814460 · PMID 29449619

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did not reach statistical significanceno p-value reported

In the present study, with the inhibition of serum ET-1 level by the ET A receptor antagonist, we found that the BQ-123 treatment tended to reduce (although did not reach statistical significance) the increased media thickness and WTTR ratio in peripheral small arteries.

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