Benefit of Adjuvant Radiotherapy for Local Control, Distant Metastasis, and Survival Outcomes in Patients with Localized Soft Tissue Sarcoma: Comparative Effectiveness Analysis of an Observational Cohort Study.

Ann Surg Oncol · 2018 · PMC5814515 · PMID 28895087

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did not reach statistical significanceno p-value reported

4 For example, a pivotal randomized controlled trial of AXRT versus observation in STS found numerically higher overall survival estimates for patients treated with AXRT, but this difference did not reach statistical significance with the 141 enrolled patients. 1 In contrast, observational cohort data for STS are copious 5 but suffer from the drawback of nonrandom treatment assignment.

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