While changes in liver Mfn2 protein levels did not reach statistical significance in the present study, the strong trend toward increased Mfn2 protein expression coupled with significant increases in Mfn1 following RYGB suggest PGC1 α may exert its effects on the liver via mitochondrial fusion.
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Effect of Roux-en-Y gastric bypass on liver mitochondrial dynamics in a rat model of obesity.
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