DEHP treatment caused a highly significant reduction of the triglyceride content in SGBS-adipocytes at d8 (DEHP 0.219 ± 0.0096 nmol/ng protein versus DMSO 0.414 ± 0.0246 nmol/ng protein) (Fig. 3A ).
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DEHP deregulates adipokine levels and impairs fatty acid storage in human SGBS-adipocytes.
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We found that ERK2 phosphorylation was significantly reduced at d8 with a strong trend of a decreased phosphorylation of ERK1 at d8, too.