An ancient conserved role for prion protein in learning and memory.

When we compared the D1 and D2 indices of the 1-year-old prp2 −/− fish to those of the 3-year-old prp2 −/− fish, we found reduced object preference among the older fish (though this did not reach statistical significance, perhaps due to the small sample size), which suggests that prp2 −/− fish exhibit age-dependent memory decline.

also in 111,027 other papers