Opposite regulation of inhibition by adult-born granule cells during implicit versus explicit olfactory learning.

Spontaneous inhibitory postsynaptic current (sIPSC) frequency recorded on M/T cells showed a trend toward increase after implicit learning (p=0.06, Kruskal-Wallis Anova followed by FDR-corrected permutation test, Enriched, n = 50 and Non-Enriched, n = 48) (for detailed statistics see Table 1 ), ( Figure 1H and Figure 1—source data 1 ) with no change in amplitude ( Table 1 , Enriched n = 48 and Non-Enriched, n = 46).

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2) What is the effect of the increase in number of adult born GCs also in the associative learning – how exactly can an addition of interneurons reduce inhibitory drive? As mentioned above, the decrease in spine numbers on the apical dendrite is barely significant.

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