Although a trend was seen for increased CVD risk for several AGE in the treatment-adjusted models, these did not reach statistical significance ( Fig. 1 B ).
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Advanced Glycation End Products, Oxidation Products, and Incident Cardiovascular Events in Patients With Type 2 Diabetes.
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Consistent with several previous longitudinal studies that have reported associations between plasma AGE and incident CVD ( 15 , 18 , 19 , 29 ), we found a nonsignificant trend for an increased risk for CVD for most AGE in the VADT. 3DG-H1 did become a significant predictor of CVD events after inclusion with MetSO in a combined model.