Although median expression was higher in the presence of the antagomir than in the miR‐mimic‐only‐transfected cells, this difference did not reach statistical significance (Fig. 3 B). miR‐424‐5p reduces IGF‐1 protein expression To determine the effect of the miRNA on secreted IGF‐1 protein levels, we transfected human myoblasts with miR‐424‐5p.
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miR-322-5p targets IGF-1 and is suppressed in the heart of rats with pulmonary hypertension.
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