Additionally, five of the nine SIV-infected macaques displayed higher levels of CCR2-positive T cells in the liver, however this trend did not reach statistical significance (p = 0.077) ( Fig 3C ).
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Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.
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0.0770
0.0770
The sentences
In addition, there was a highly significant increase in CCR2-monocytes/macrophages that express the inflammatory marker, CD16, again providing evidence for CCR2-associated expansion of inflammatory CD16+ monocyte/macrophages in the livers of SIV-infected macaques.