After 12 months, uMCP1 excretion was lower in the tolvaptan than in the placebo group, but did not reach statistical significance until 24 (13.8 ± 3.4%, P<0.0001) and 36 months (14.4 ± 3.7%, P<0.0001).
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Tolvaptan suppresses monocyte chemotactic protein-1 excretion in autosomal-dominant polycystic kidney disease.
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