Prognostic Significance of Vascular Endothelial Growth Factor (VEGF) and Her-2 Protein in the Genesis of Cervical Carcinoma.

The difference in VEGF expression between different grades of a tumour did not reach statistical significance ( p > 0.05) ( Table 1 ), and intensity of expression was high in poorly differentiated carcinoma as compared to well and moderately differentiated carcinoma.

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Lastly, another study reported similar findings where benign, premalignant and malignant cervical tissues showed a highly significant correlation between the expression of the epidermal growth factor receptor (EGF-R), the oncogene product of c–erbB-2 and the histological grade of the lesion [ 34 ].

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