BACE1 deletion in the adult mouse reverses preformed amyloid deposition and improves cognitive functions.

J Exp Med · 2018 · PMC5839766 · PMID 29444819

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did not reach statistical significanceno p-value reported

On day 3 for the cue test, the freezing time in BACE1 fl/fl/5xFAD mice was also reduced but did not reach statistical significance when compared with the other three genotypes of mice ( Fig. 7 ).

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