Can bacterial virulence factors predict antibiotic resistant <i>Helicobacter pylori</i> infection?

While there was a significant association between the less virulent vacA s2 genotype and fluoroquinolone resistance when all patients were included [15% ( n = 17/113) vs 30.8% ( n = 16/52); χ 2 = 5.5; P = 0.02; Pearson χ 2 test; Figure 4A ], this did not reach statistical significance in treatment naïve patients (Figure 4B ) or those previously treated (Figure 4C ).

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