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Microglial activation, white matter tract damage, and disability in MS.

Neurol Neuroimmunol Neuroinflamm · 2018 · PMC5840890 · PMID 29520366

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In the evaluation of Gd+ lesion–associated ROIs, the mean perilesional binding in patients with SPMS appeared to be higher compared with patients with RRMS, but the difference did not reach statistical significance because of the low number of patients (n = 4 + 4) and high variance ( figure 2C ).

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