Novel smac mimetic APG-1387 elicits ovarian cancer cell killing through TNF-alpha, Ripoptosome and autophagy mediated cell death pathway.

J Exp Clin Cancer Res · 2018 · PMC5848599 · PMID 29530056

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showed a trendno p-value reported

The recent trials of birinapant and DEBIO1143 (AT-406) reported patients showed a trend towards increased circulating TNF-α [ 15 , 36 ].

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