Most bicarbonate secretion by Calu-3 cells is mediated by CFTR and independent of pendrin.

IL‐4 alone did not alter fluid secretion by parental Calu‐3 monolayers, however, there was a trend toward higher forskolin‐stimulated secretion that did not reach statistical significance at P < 0.05 (but did at P < 0.1, Fig. 8 D; n = 4, P = 0.08).

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