weakly significantP = 0.041
Comparisons between A 6 ratios with A 9 and A 12 ratios (in codons 4 and 5) show weakly significant A content variation at these synonymous sites ( P = 0.041, KruskalWallis rank-sum test), however pairwise comparisons between A ratios indicate the second codon is not significantly different in terms of synonymous A enrichment ( A 6 – A 9 : P = 0.973, A 6 –A 12 : P = 0.057, A 9 – A 12 : P = 0.096, pairwise Tukey–Kramer tests).