Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance.

Hum Reprod Update · 2017 · PMC5850862 · PMID 27827818

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did not reach statistical significanceP = 0.13not close (p > 0.1)

Post-warming cryosurvival rates of vitrified blastocysts were also higher than those observed with slow-freezing, but did not reach statistical significance (RR = 1.25: 95% CI: 0.93–1.67; P = 0.13; two RCTs; 1084 blastocysts; I 2 = 82.2%, moderate quality evidence).

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