Barely Significant
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Efficacy of Diacetate Esters of Macular Carotenoids: Effect of Supplementation on Macular Pigment.

J Nutr Metab · 2018 · PMC5852865 · PMID 29686895

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Effect of Gender on Change in MPOD Presupplementation MPOD was lower for the female subjects in the combined groups compared with the males but did not quite reach statistical significance.

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a negative trendno p-value reported
Effect of Presupplementation MPOD on Change in MPOD There was a negative trend between the change in MPOD and the presupplementation MPOD for each group as well as for the combined groups.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.