Consistent hypersocial behavior in mice carrying a deletion of <i>Gtf2i</i> but no evidence of hyposocial behavior with <i>Gtf2i</i> duplication: Implications for Williams-Beuren syndrome and autism spectrum disorder.

Brain Behav · 2018 · PMC5853625 · PMID 29568691

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0.0610

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

approached significancep = .061so close (0.05 < p ≤ 0.1)

Overall, the Gtf2i +/− mice spent more time in the urine zone ( M = 61.5 s, SD = 27.3) than the Gtf2i +/+ mice ( M = 41.5, SD = 27.7); however, this difference only approached significance ( t (27) = −1.96, p = .061). 3.5 Operant paradigms 3.5.1 Social motivation paradigm Both genotypes learned to associate lever pressing with a social reward during the shaping phase of the social motivation paradigm.

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