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Clinical Pharmacokinetics and Pharmacodynamics of the Epidermal Growth Factor Receptor Inhibitor Panitumumab in the Treatment of Colorectal Cancer.

Clin Pharmacokinet · 2018 · PMC5856878 · PMID 28853050

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a positive trendno p-value reported
12.5 months; HR 0.92, 95% CI 0.78–1.10, p = 0.366), a positive trend was observed.

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showed a trendno p-value reported
also showed a trend toward improved OS in patients who were WT RAS and BRAF in the FOLFIRI plus panitumumab arm compared with the FOLFIRI plus bevacizumab arm [ 46 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.