Under basal conditions at 1 Hz pacing frequency, the developed force of the hECTs infected with shCXCR7 or shCXCR4 and shCXCR7 showed a trend to be higher than Control and shScramble ( Fig. 5A ).
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CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response.
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