IFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes.

BMC Pulm Med · 2018 · PMC5861655 · PMID 29562888

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COPD patients exposed to rhinovirus consistently showed a trend towards less IFNL expression in bronchoalveolar lavage fluid [ 25 ] and in animal models it has been shown that IFNL plays a role in viral (influenza A, coronavirus and rotavirus) modulation [ 6 ].

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