Impact of creatinine clearance on outcomes in patients with non-valvular atrial fibrillation: a subanalysis of the J-RHYTHM Registry.

Eur Heart J Qual Care Clin Outcomes · 2018 · PMC5862022 · PMID 28950373

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0520

boldest claim

The sentences

a significant trendP < 0.001actually significant

There was a significant trend for the four events, and consequently, for composite events among the four CrCl groups ( P < 0.001 for trend).

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marginal significanceP = 0.052so close (0.05 < p ≤ 0.1)

However, this was not the case in the present study, in which the HR of CrCl values of <30 mL/min showed only marginal significance for thromboembolic events in the univariate analysis ( P = 0.052, Table 3 ), though the P -value exceeded 0.30 in the multivariate analysis ( Table 4 ).

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