Elevated Aromatase (CYP19A1) Expression Is Associated with a Poor Survival of Patients with Estrogen Receptor Positive Breast Cancer.

Horm Cancer · 2018 · PMC5862917 · PMID 29363090

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0680

boldest claim

The sentences

highly significantP = 3.1 × 10 −5actually significant

In ER-positive patients, highly significant differences between patients with high vs. low CYP19A1 expression were observed with respect to OS ( P = 3.1 × 10 −5 ; Fig. 4 d), DFS ( P = 2.1 × 10 −4 ; Fig. 4 e), and MFS ( P = 1.5 × 10 −6 ; Fig. 4 f).

also in 132,142 other papers

showed a trendP = 0.068so close (0.05 < p ≤ 0.1)

Unselected patients with high CYP19A1 expression showed a trend towards decreased lung-MFS ( P = 0.068) and bone-MFS ( P = 0.072) compared to patients with low CYP19A1 expression, whereas no association was found in the analysis of liver-MFS ( P = 0.605; Supplementary Fig. 1 ).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.