In this experiment, expression of autophagy markers showed a trend consistent with reports in the existing literature, and mTORC1 activity in the injured spinal cord of rats fed a high-n-3 PUFA diet was obviously reduced ( Fig. 4 ), while LC3-II protein expression was enhanced.
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Inhibition of mammalian target of rapamycin complex 1 signaling by n-3 polyunsaturated fatty acids promotes locomotor recovery after spinal cord injury.
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