Upregulation of Glucose Uptake and Hexokinase Activity of Primary Human CD4+ T Cells in Response to Infection with HIV-1.

Viruses · 2018 · PMC5869507 · PMID 29518929

Europe PMC DOI

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failed to reach significanceno p-value reported

The increased lactic acid production of HIV-1 infected cells failed to reach significance in this experiment ( Figure 3 C).

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highly significantno p-value reported

The investigation of glycolytic enzymes demonstrated activation-dependent expression of hexokinases HK1 and HK2 in human CD4+ T cells, and a highly significant increase in cellular hexokinase enzyme activity in response to infection with HIV-1.

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failed to reach statistical significanceno p-value reported

This was highly significant for GLUT1, GLUT3, and GLUT4, but failed to reach statistical significance for GLUT6.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.